Protease Inhibitors and Phosphatase Inhibitors
Medchemexpress LLC P38 MAP Kinase Inhibitor VI | 421578-46-3 | 98.0% | C16H13FN2OS2 | 5 MG
P38 MAP Kinase Inhibitor VI (compound c32) is a p38 MAPK inhibitor with an inhibition rate of 24%. It is intended for research use only and is not sold to patients.
- Inhibits p38 MAPK.
- High purity (98.0%).
Sigma Aldrich Fine Chemicals Biosciences Complete, EDTA-free Protease Inhibitor Cocktail, 20 tablets
Complete, EDTA-free Protease Inhibitor Cocktail, 20 tablets.
Cayman Chemical Syk InhIbItr II 1mg
A cell-permeable, selective, and reversible inhibitor of Syk (IC50 = 41 nM); prevents FcεRI-mediated 5-HT release in RBL-2H3 cells in vitro (IC50 = 460 nM) and inhibits passive cutaneous anaphylaxis reactions in mice (ID50 = 13.2 mg/kg, s.c.)
Medchemexpress LLC BRM/BRG1 ATP Inhibitor-2 | 2368900-77-8 | 99.7% | C20H20N4O2S2 | 100 MG
BRM/BRG1 ATP Inhibitor-2 is a BRG1/BRM ATPase inhibitor for the research of BAF-related disorders. It is for research use only and not sold to patients.
- BRG1/BRM ATPase inhibitor
- For research of BAF-related disorders
- Available as a white to off-white solid
- Molecular weight is 412.53
- For research use only
AG Scientific Inc Protease Inhib V No Anml EDTA
Protease Inhibitor Cocktail V, EDTA-Free, Animal-Free is a mixture of four protease inhibitors which has been optimized for the inhibition of serine, cysteine but not metalloproteases. For applications that require animal-free reagents. 1X stock solution contains: 500 μM AEBSF HCl 150 nM Aprotinin, recombinant (animal-free) 1μM E-64 1μM Leupeptin hemisulfate Preparation: Reconstitute each vial with 1 mL water to obtain a 100X concentrated stock solution. Dilute with 100 mL solution to achieve 1X stock solution. Soluble in water, aqueous buffers, or add directly to extraction media.
![Biolegend Alexa Fluor 647 anti-PTEN Phospho (Ser380) [A22005D]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: ICFC, IHC-P; Size: 25 μg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502723711.png-250.jpg)
Biolegend Alexa Fluor 647 anti-PTEN Phospho (Ser380) [A22005D]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: ICFC, IHC-P; Size: 25 μg
Alexa Fluor 647 anti-PTEN Phospho (Ser380) [A22005D]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: ICFC, IHC-P; Size: 25 μg
Cayman Chemical Aurora A InhIbItr I 1mg
A potent and selective inhibitor of Aurora A kinase (IC50s = 3.4 and 3,400 nM for Aurora A and Aurora B, respectively); prevents centrosome separation and reduces phosphorylated Aurora A, but not phosphorylated histone H3, levels at the centrosomes; reduces the proliferation of HCT116 and HT-29 colorectal carcinoma cells in vitro (IC50s = 0.19 and 2.9 μM, respectively)
Selleck Chemical LLC FGFR1/DDR2 inhibitor 1
FGFR1/DDR2 inhibitor 1 is an inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoidin domain receptor 2 (DDR2)
Invivogen TLR9 ANTAGONIST - CLASS B INHI
Toll-Like Receptor 9 (TLR9) detects unmethylated CpG dinucleotides in bacterial or viral DNA inducing strong immunostimulatory effects.TLR9 activation can be mimicked by synthetic phosphorothioate-stabilized oligodeoxynucleotides (ODN) containing immune stimulatory CpG motifs.Studies suggest the existence of DNA sequences that can neutralize the stimulatory effect of CpG ODNs.ODN INH-18 is a linear and class R (restricted) inhibitory ODN. It contains an inhibitory DNA motif consisting of two nucleotide triplets, a proximal CCT and a more distal GGG, spaced from each other by four nucleotides.ODN INH-18 is a potent inhibitor of TLR9-induced B cells and macrophages [1]. ODN INH-18 strongly blocks TLR9 activation in both human and mouse TLR9-expressing cells. INVIVOGEN mfg# TLRL-INH18
Mitegen Sodium fluoride, 0.5M, 100 ml, CAS # 7681-49-4
Use our stock solutions directly or as a component in solutions you create in your own lab. We prepare our stock solutions using high quality raw materials, ASTM Type 1 water, and sterile packaging.�Our stock solutions are intended for Research and Development Use Only.
Enzo Life Sciences Pepstatin A (synthetic) (100mg). CAS: 26305-03-3
Protease inhibitor. Inhibitor of aspartate (acid) proteases, including pepsin, cathepsin D, renin, chymosin, bacterial aspartic proteinases and HIV proteases. Efficiently inhibits Fcγ receptor induction by IFN-γ. Blocks the endocytic pathway followed by an antibody when it enters the cell at the level of early endosomal compartments, resulting in inhibition of autoantigen presentation or viral transmission. Suppresses p-53-dependent apoptosis in lymphoid cells as well as TNFα-induced apoptosis in U937 cells. Inhibits degradation of autophagic cargo inside autophagolysosomes. Alternative name: Iva-Val-Val-Sta-Ala-Sta, i-Valeryl-L-Val-L-Val-AHMHA-L-Ala-AHMHA. Formula: C34H63N5O9. MW: 685.9. Purity: ≥98% (HPLC). Appearance: White to off-white solid. MI: 14: 7147. Solubility: Soluble in DMSO (10mg/ml), methanol (1mg/ml) or acetic acid. Long Term Storage: -20°C. Use/Stability: Stable for at least 2 years after receipt when stored at -20°C. Handling: Protect from light.
Sigma Aldrich Fine Chemicals Biosciences Protease Inhibitor Cocktail for plant cell and tissue extracts, DMSO solution | MFCD00677817 | 5ML
Protease Inhibitor Cocktail for plant cell and tissue extracts, DMSO solution | MFCD00677817 | 5ML
Cayman Chemical ACE2 InhIbItr Screeng as 96Wel
Cayman’s ACE2 Inhibitor Screening Assay Kit provides a robust and EAsy-to-use platform for testing potential inhibitors of human ACE2. The assay uses an ACE2-specific fluorogenic substrate, Mca-APK (Dnp). ACE2 cleaves this substrate generating free Mca, which can be EAsily quantified using a fluorescence plate reader at excitation and emission wavelengths of 320 and 405 nm, respectively. The potent and reversible ACE2 inhibitor MLN-4760 is included as a positive control. Human ACE2 plays an important role in regulating blood pressure. It is also known to bind SARS-CoV-2 spike. This assay can be used as a counter-screen for potential drug candidates to ensure they do not interfere with the normal physiological functions of ACE2.
Cayman Chemical C1 InhIbItr PolycLNal ntIb
An isoflavonoid with antioxidant activity scavenges peroxynitrite nitric oxide radicals and total ROS (IC50s 1.36 1.13 and 6.51 UM respectively)
Cayman Chemical PTP InhIbItr II 25g
A cell-permeable inhibitor of the catalytic domain of SHP-1, SHP-1(ΔSH2) (Ki = 128 µM)